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Updated: May 14, 2026

Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter
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Quantification of three DNA Lesions by Mass Spectrometry and Assessment of Their Levels in Tissues of Mice Exposed to Ambient Fine Particulate Matter

Published on: May 29, 2019

DNAにおける酸化性チミン変異:水線媒介によるプロトン結合電子移転

Robert N Barnett1, Joshy Joseph, Uzi Landman

  • 1School of Physics, Georgia Institute of Technology, Atlanta, Georgia 30332-0430, USA.

Journal of the American Chemical Society
|February 21, 2013
PubMed
まとめ

DNAの酸化により,チミンの突然変異が起こります. デュテラテッドチミン実験と量子計算では,速度の決定段階におけるC−H結合の割れ込みを含む,陽子結合電子伝送 (PCET) が鍵となることが明らかになった.

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