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Updated: May 14, 2026

Development and Application of Rapamycin-regulated Tyrosine Phosphatases
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定量的なフォスフォプロテオミクスは,mTORC1が新たなピリミジン合成を活性化することを明らかにしています

Aaron M Robitaille1, Stefan Christen, Mitsugu Shimobayashi

  • 1Biozentrum, University of Basel, Basel, Switzerland.

Science (New York, N.Y.)
|February 23, 2013
PubMed
まとめ

ラパミシン (mTOR) 経路の哺乳類の標的は,細胞の成長を調節する. この研究は,mTORC1が,CADをリン酸化することによってピリミジン合成を刺激し,細胞増殖を促進することを明らかにしています.

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