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Updated: May 14, 2026

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
09:51

Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling

Published on: July 26, 2017

最小の"自己"ペプチドは,ファゴサイトクリアランスを阻害し,ナノ粒子の配送を強化します

Pia L Rodriguez1, Takamasa Harada, David A Christian

  • 1Molecular and Cell Biophysics and NanoBioPolymers Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA.

Science (New York, N.Y.)
|February 23, 2013
PubMed
まとめ

研究者は,ヒトのCD47から"自己"ペプチドを設計し,免疫細胞がナノ粒子をクリアするのを防止しました. この戦略は,ナノ粒子の循環を促進し,腫瘍への薬物および染料の投与を改善します.

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Polyethyleneimine-coated Iron Oxide Nanoparticles as a Vehicle for the Delivery of Small Interfering RNA to Macrophages In Vitro and In Vivo09:36

Polyethyleneimine-coated Iron Oxide Nanoparticles as a Vehicle for the Delivery of Small Interfering RNA to Macrophages In Vitro and In Vivo

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