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Updated: May 13, 2026

Harnessing the Bioorthogonal Inverse Electron Demand Diels-Alder Cycloaddition for Pretargeted PET Imaging
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Published on: February 3, 2015

レドックス媒介のベルグマンサイクルを用いて,二重作用のメタロエネディネの治療薬の開発を目指す

Sarah E Lindahl1, Hyunsoo Park, Maren Pink

  • 1Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA.

Journal of the American Chemical Society
|February 26, 2013
PubMed
まとめ

安定したプラチナ (((0) メタロエネディイン複合体,Pt (((dppeb) 2は,酸化時に効率的なリドックス媒介のベルグマン循環を経る. この反応によりシスプラチンのような副産物が生成され,双重作用のメタロエネダイネ療法薬の新たな戦略が提案されます.

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