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ヒトの転写開始における重要なステップの構造的視覚化

Yuan He1, Jie Fang, Dylan J Taatjes

  • 1Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA.

Nature
|March 1, 2013
PubMed
まとめ

研究者は,冷凍電子顕微鏡を用いて,転写開始因子の組み立てを視覚化しました. これは,転写因子IIF (TFIIF) が複合体を安定させ,TFIIH (転写因子II H) が正確な遺伝子発現のためにDNAを開く方法を示しています.

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