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関連する概念動画

What is Cell Signaling?02:03

What is Cell Signaling?

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
What is Cell Signaling?02:03

What is Cell Signaling?

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
Overview of Cell Signaling01:23

Overview of Cell Signaling

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
Overview of Cell Signaling01:23

Overview of Cell Signaling

Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate with the environment.
Cells respond to many types of information, often through receptor proteins positioned on the membrane. For example, skin cells respond to and transmit touch...
Diversity in Cell Signaling Responses01:22

Diversity in Cell Signaling Responses

The physiological function of a cell and cellular communication are outcomes of a range of extrinsic signals, intracellular signaling pathways, and cellular responses. No two cell types express the same repertoire of signaling components. Receptors are highly selective for their cognate ligands, but once activated, they can alter multiple cellular processes such as DNA transcription, protein synthesis, and metabolic activity. 
Graded and Abrupt Responses
Some signaling systems generate...
Intracellular Signaling Cascades01:24

Intracellular Signaling Cascades

Once a ligand binds to a receptor, the signal is transmitted through the membrane and into the cytoplasm. The continuation of a signal in this manner is called signal transduction. Signal transduction only occurs with cell-surface receptors, which cannot interact with most components of the cell, such as DNA. Only internal receptors can interact directly with DNA in the nucleus to initiate protein synthesis. When a ligand binds to its receptor, conformational changes occur that affect the...

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Updated: May 13, 2026

Optogenetic Signaling Activation in Zebrafish Embryos
07:18

Optogenetic Signaling Activation in Zebrafish Embryos

Published on: October 27, 2023

信号ダイナミクスを通してセルラー情報のエンコーディングとデコーディング.

Jeremy E Purvis1, Galit Lahav

  • 1Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|March 5, 2013
PubMed
まとめ
この要約は機械生成です。

細胞は分子信号のタイミングを使って情報を伝達する. このレビューでは,これらのダイナミックなシグナル伝達パターンが,細胞の反応と潜在的な疾患治療をどのように制御するかを調査します.

さらに関連する動画

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
08:00

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation

Published on: October 4, 2024

An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions
07:59

An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions

Published on: March 22, 2018

関連する実験動画

Last Updated: May 13, 2026

Optogenetic Signaling Activation in Zebrafish Embryos
07:18

Optogenetic Signaling Activation in Zebrafish Embryos

Published on: October 27, 2023

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation
08:00

Spatiotemporal Control of Protein Activity through Optogenetic Allosteric Regulation

Published on: October 4, 2024

An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions
07:59

An Optogenetic Method to Control and Analyze Gene Expression Patterns in Cell-to-cell Interactions

Published on: March 22, 2018

科学分野:

  • 細胞生物学 細胞生物学
  • 分子シグナル伝達です.
  • システム生物学 システム生物学

背景:

  • 新興の研究では,細胞通信における時間動態の重要な役割が強調されています.
  • 信号分子の時間の経過における行動は,重要な情報伝達体としてますます認識されています.

研究 の 目的:

  • 信号ネットワークのダイナミクスに関する現在の理解をレビューする.
  • 時間のパターンが刺激情報をコードし,細胞の結果に影響を与える方法に関する新興の原則を特定する.
  • これらのダイナミクスを形作り,解釈するネットワーク構造を探求する.

主な方法:

  • 信号ネットワークのダイナミクスに関する文献レビュー.
  • 時間のパターンにおける刺激のコーディングを統制する原理の分析.
  • ネットワーク構造が信号ダイナミクスと細胞応答にどのように影響するかを調べる.

主要な成果:

  • 細胞情報は,信号分子の時間パターンにコード化されています.
  • 信号ダイナミクスは,細胞の反応と結果に大きな影響を与えます.
  • 分子ネットワークのアーキテクチャは,ダイナミックな信号の形成と解釈において重要な役割を果たします.

結論:

  • 細胞の情報伝達は,信号分子のダイナミクスに依存している.
  • これらのダイナミクスを理解することは,病気の治療のための潜在的な応用を提供します.
  • ダイナミック・シグナリングは,細胞の情報処理の基本的側面を表しています.