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Updated: May 13, 2026

RNA-based Reprogramming of Human Primary Fibroblasts into Induced Pluripotent Stem Cells
11:38

RNA-based Reprogramming of Human Primary Fibroblasts into Induced Pluripotent Stem Cells

Published on: November 26, 2018

Jmjd3はINK4a/Arfの発現をアップレギュレーションし,UbiquitinationのためにPHF20をターゲットにすることで再プログラミングを阻害します

Wei Zhao1, Qingtian Li, Stephen Ayers

  • 1Center for Inflammation and Epigenetics, The Methodist Hospital Research Institute, Houston, TX 77030, USA.

Cell
|March 5, 2013
PubMed
まとめ

Jmjd3は,誘発性多能幹細胞 (iPSC) に細胞の再プログラミングを否定的に調節する. その欠如は,iPSCの生成を強化し,その存在はそれを阻害し,新しいJmjd3-PHF20規制軸を明らかにします.

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Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry

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Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers10:28

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers

Published on: September 20, 2018

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