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Updated: May 7, 2026

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 27, 2013

誘導塩感受キナーゼSGK1による病原性TH17細胞の誘導

Chuan Wu1, Nir Yosef, Theresa Thalhamer

  • 1Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nature
|March 8, 2013
PubMed
まとめ

血清グルココルチコイドキナーゼ1 (SGK1) は,高塩分ダイエットと炎症性TH17細胞の発達を関連付けています. このSGK1経路はIL-23受容体の発現を促進し,自己免疫と組織炎症を誘発する.

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In Vitro Differentiation of Naive CD4+ T Cells into Pathogenic Th17 Cells in Mouse

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