T

Sven Malchow1, Daniel S Leventhal, Saki Nishi

  • 1Department of Pathology, University of Chicago, Chicago, IL 60637, USA.

Science (New York, N.Y.)
|March 9, 2013
PubMed
まとめ

研究者らは,腫瘍特異的ではなく,前立腺に関連する抗原を標的にする特定の種類の調節性T細胞 (Treg) を発見した. これらの細胞は,自己免疫調節経路 (Aire) を経由して,胸腺に発達し,前立腺腫瘍で発見されます.

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T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...