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Updated: May 13, 2026

Separation of the Cell Envelope for Gram-negative Bacteria into Inner and Outer Membrane Fractions with Technical Adjustments for Acinetobacter baumannii
10:24

Separation of the Cell Envelope for Gram-negative Bacteria into Inner and Outer Membrane Fractions with Technical Adjustments for Acinetobacter baumannii

Published on: April 10, 2020

合成グラム陰性脂質IIから交結ペプチドグリカンを形成する

Matthew D Lebar1, Tania J Lupoli, Hirokazu Tsukamoto

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Journal of the American Chemical Society
|March 14, 2013
PubMed
まとめ

研究者は,グラム陰性ペプチドグリカン (PG) アセンブリのためのバクテリア細胞壁前駆体Lipid IIを合成した. この研究では,m-DAP残基は,トランスペプチダース活性にインビトロにおいて決定的に重要であり,ネイティブ構造に似たPGの生産を可能にしました.

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