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Updated: May 6, 2026

Recombineering Homologous Recombination Constructs in Drosophila
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DNAの二重鎖の断裂でクロマチンの改造

Brendan D Price1, Alan D D'Andrea

  • 1Division of Genomic Stability and DNA Repair, Department of Radiation Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA.

Cell
|March 19, 2013
PubMed
まとめ

DNAの二重鎖断裂 (DSBs) は,染色体の改造を誘発し,DNA修復に不可欠なオープン構造を作り出します. このプロセスは修復タンパク質へのアクセスを促進し,効率的な哺乳類のDSB修復を可能にします.

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