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Updated: May 13, 2026

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions
10:58

PIP-on-a-chip: A Label-free Study of Protein-phosphoinositide Interactions

Published on: July 27, 2017

カチオン-π相互作用は,フォスファディチルニノシトール固有のフォスフォリファースCの脂質固有のアンカーとして作用する

Cédric Grauffel1, Boqian Yang, Tao He

  • 1Department of Molecular Biology, UniResearch, University of Bergen, Bergen, Norway.

Journal of the American Chemical Society
|March 20, 2013
PubMed
まとめ

バシルス・トゥリンギエンシス・フォスファディチルニノシトール固有のフォスフォリパゼC (PI-PLC) は,チロシン残基とフォスファディチルコレンのヘッドグループ間のカチオン-π相互作用を使用して,膜結合を行います. このメカニズムは,アンフィトロピクタンパク質が細胞表面上のズウィテリオン性脂質を認識する方法を説明しています.

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