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Updated: May 5, 2026

Analysis of the c-KIT Ligand Promoter Using Chromatin Immunoprecipitation
09:40

Analysis of the c-KIT Ligand Promoter Using Chromatin Immunoprecipitation

Published on: June 27, 2017

7.2K

TGF-β1結合タンパク質:TGF-β1の大型潜伏複合体の構成要素で,複数の繰り返し配列を有する

T Kanzaki1, A Olofsson, A Morén

  • 1Ludwig Institute for Cancer Research, Biomedical Center, Uppsala, Sweden.

Cell
|June 15, 1990
PubMed
まとめ

研究者らは,潜伏しているTGF-β1複合体の構成要素であるTGF-β1結合タンパク質 (TGF-β1-BP) をクローン化し,特徴づけました. その独特の構造と結合特性が分析され,TGF-β1の調節に関する洞察が明らかになった.

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Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells06:54

Studying TGF-β Signaling and TGF-β-induced Epithelial-to-mesenchymal Transition in Breast Cancer and Normal Cells

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Analysis of Transforming Growth Factor ß Family Cleavage Products Secreted Into the Blastocoele of Xenopus laevis Embryos06:57

Analysis of Transforming Growth Factor ß Family Cleavage Products Secreted Into the Blastocoele of Xenopus laevis Embryos

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関連する概念動画

Transcription Factors02:16

Transcription Factors

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General Transcription Factors01:30

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TGF - β Signaling Pathway01:16

TGF - β Signaling Pathway

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Activation and Inactivation of G Proteins

Heterotrimeric G proteins are guanine nucleotide-binding proteins. As the name suggests, heterotrimeric G proteins are composed of three subunits: alpha, beta, and gamma. They remain GDP-bound or GTP-bound inside the cells and switch between inactive/active states. The Gα subunit possesses the nucleotide-binding pocket that binds guanine nucleotides and switches between GDP or GTP-bound states. In contrast, the Gꞵ and Gγ subunits are always bound together with high...
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Integrins01:10

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Animal and protozoan cells do not have cell walls to help maintain shape and provide structural stability. Instead, these eukaryotic cells secrete a sticky mass of carbohydrates and proteins into the spaces between adjacent cells. This network of proteins and molecules is called an extracellular matrix or ECM.
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