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Updated: May 13, 2026

Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions
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Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions

Published on: January 26, 2024

免疫グロブリン型ドメインの無形タンパク質集積のための機械的モデル

Madeleine B Borgia1, Adrian A Nickson, Jane Clarke

  • 1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.

Journal of the American Chemical Society
|March 21, 2013
PubMed
まとめ

アルツハイマー病などの疾患に関連したタンパク質の集積は,典型的な核形成モデルに従わない場合があります. 私たちの研究は,集積が活性化された二次体を通して起こることを示唆しており,その速度は,集積された表面積に依存しています.

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