関連する実験動画

Updated: May 13, 2026

Establishment and Validation of a Rat Model of Pulmonary Arterial Hypertension Associated with Pulmonary Fibrosis
07:11

Establishment and Validation of a Rat Model of Pulmonary Arterial Hypertension Associated with Pulmonary Fibrosis

Published on: May 23, 2025

ヌトリン-3aによる肺p53の活性化は,実験的な肺高血圧を予防し,逆転させます

Nathalie Mouraret1, Elisabeth Marcos, Shariq Abid

  • 1Hôpital Henri Mondor, Service de Physiologie-Explorations Fonctionnelles, Créteil, France.

Circulation
|March 21, 2013
PubMed
まとめ

Nutlin-3aは,肺動脈の滑らかな筋肉細胞の細胞衰老を誘導し,細胞増殖を制限することによって,肺高血圧 (PH) の潜在的な治療を提供します. このプロセネセンスの治療は,PHの重症度および関連する合併症を軽減することに有望であることが示されています.

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