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Updated: May 13, 2026

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
06:44

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding

Published on: March 24, 2018

超膜ハロゲン結合カスケード

Andreas Vargas Jentzsch1, Stefan Matile

  • 1Department of Organic Chemistry, University of Geneva, Geneva, Switzerland.

Journal of the American Chemical Society
|March 23, 2013
PubMed
まとめ

ハロゲン結合ドナーの線形配列は,硬質の支架上にあり,膜を横断するアニオン輸送を大幅に強化します. このブレークスルーは,以前の設計の限界を克服し,超膜アニオンホッピングの優れた活動と前例のない協力性を達成しました.

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Rab Cascades

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Halogenation of Alkenes

Halogenation is the addition of chlorine or bromine across the double bond in an alkene to yield a vicinal dihalide. The reaction occurs in the presence of inert and non-nucleophilic solvents, such as methylene chloride, chloroform, or carbon tetrachloride.
Consider the bromination of cyclopentene. Molecular bromine is polarized in the proximity of the π electrons of cyclopentene. An electrophilic bromine atom adds across the double bond, forming a cyclic bromonium ion intermediate.
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Formation of Halohydrin from Alkenes

An alkene, such as propene, reacts with bromine in the presence of water to yield a halohydrin. Halohydrins contain a halogen and a hydroxyl group attached to adjacent carbons. When the halogen is bromine, it is called a bromohydrin, while a chlorohydrin has chlorine as the halogen.
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SNAREs and Membrane Fusion

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Electrophilic 1,2- and 1,4-Addition of X2 to 1,3-Butadiene

Electrophilic addition of halogens to alkenes proceeds via a cyclic halonium ion to form a 1,2-dihalide or a vicinal dihalide.
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Multi-pass Transmembrane Proteins and β-barrels

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α-Helix containing multi-pass transmembrane proteins
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