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Updated: May 13, 2026

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram
12:21

Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram

Published on: November 27, 2016

セロトニン受容体における機能的選択性の構造的特徴

Daniel Wacker1, Chong Wang, Vsevolod Katritch

  • 1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|March 23, 2013
PubMed
まとめ

リスルギン酸ダイエチラミドおよび関連化合物は,5-HT2B受容体でバイアス信号を発し,β-アレスティン経路を活性化します. 構造研究は,Gタンパク質結合受容体 (GPCRs) のこの機能的選択性の基礎を明らかにします.

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Rapid In Situ Hybridization using Oligonucleotide Probes on Paraformaldehyde-prefixed Brain of Rats with Serotonin Syndrome

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