関連する実験動画
Updated: May 13, 2026

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Quantifying Abdominal Pigmentation in Drosophila melanogaster
Published on: June 1, 2017
遺伝子調節モジュールの進化を通して,ハエの色素の出現と多様化
Laurent Arnoult1, Kathy F Y Su, Diogo Manoel
1Aix-Marseille Université, CNRS, UMR 7288, Institut de Biologie du Développement de Marseille-Luminy, 13288 Marseille cedex 9, France.
まとめ
新しい遺伝子調節モジュールは,ハエのダークウィングの色素斑点の出現を可能にしました. この調節器の後の変更により,
科学分野:
- 進化生物学の進化生物学について
- 遺伝学 遺伝学とは
- 発達生物学 発達生物学とは
背景:
- 形態学的進化は,しばしば新しい特徴の出現と多様化を伴う.
- これらの進化のステップ,特に色素の遺伝的基盤は,ほとんど不明のままである.
研究 の 目的:
- ハエの翼の色素化パターンの起源と多様化の背後にある遺伝的メカニズムを調査する.
- 翼の斑点の進化に起因する遺伝子のネットワークを特定する.
主な方法:
- 遺伝子調節モジュールアセンブリの分析.
- 染色体遺伝子の進化とその転写調節体の進化を研究する.
- 遺伝子発現パターンの変化を調べる.
主要な成果:
- 新しい遺伝子調節モジュールは,暗い翼の色素斑点の出現を促進しました.
- 配色遺伝子は,共有された転写レギュレータに反応するようにコオプトされた.
- 翼のスポットパターンの多様化は,レギュレータの表現の変化によって発生しました.
結論:
- 特徴の出現と多様化のための遺伝的変化は,遺伝的ネットワーク内で分離されています.
- 遺伝子調節ネットワークを理解することは,進化過程の解読の鍵です.
- この研究は,新しい特性の進化の遺伝的基盤のモデルを提供します.
関連する概念動画
Gene Duplication and Divergence
The seminal work of Ohno in 1970 popularized the idea of gene duplication and divergence. DNA sequence comparison studies reveal that a large portion of the genes in bacteria, archaebacteria, and eukaryotes was generated by gene duplication and divergence, indicating its critical role in evolution.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
The duplicated copies of the gene are called Paralogs. Paralogs with similar sequences and functions form a gene family. Across several species, a large number of gene families are characterized.
Position-effect Variegation
In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
Epistasis
In addition to multiple alleles at the same locus influencing traits, numerous genes or alleles at different locations may interact and influence phenotypes in a phenomenon called epistasis. For example, rabbit fur can be black or brown depending on whether the animal is homozygous dominant or heterozygous at a TYRP1 locus. However, if the rabbit is also homozygous recessive at a locus on the tyrosinase gene (TYR), it will have an unshaded coat that appears white, regardless of its TYRP1...
Pigmentation
The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Background and Environment Affect Phenotype
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
Evolution of New Traits in Microbes
Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...

