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Updated: May 3, 2026

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins
16:10

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

Published on: March 22, 2012

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アゴニスティックリガンドによって誘発されたトール型受容体8ジメルの構造的再編成

Hiromi Tanji1, Umeharu Ohto, Takuma Shibata

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Science (New York, N.Y.)
|March 23, 2013
PubMed
まとめ

リガンドによるトール型受容体8 (TLR8) の活性化が構造的に特徴づけられた. リンガンド結合はTLR8ジメルの再編成を誘導し,下流の先天性免疫シグナリングを可能にします.

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