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Updated: May 12, 2026

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
07:10

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay

Published on: September 14, 2014

一般的に,広範囲で強力なHIV-1中和のために,免疫グロブリン構造体の体内変異が求められます

Florian Klein1, Ron Diskin, Johannes F Scheid

  • 1Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

Cell
|April 2, 2013
PubMed
まとめ

HIV-1に対する最も広範に中和する抗体 (bNAbs) は,抗原結合ループだけでなく,そのフレームワーク領域 (FWR) の変異を必要とします. これらのFWR変異は,HIV-1ワクチンの開発に不可欠な抗体の効能と幅を高めます.

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Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding10:50

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding

Published on: September 15, 2010

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses14:23

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

Published on: August 31, 2014

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