Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Meristems and Plant Growth02:36

Meristems and Plant Growth

36.3K
Plants grow throughout their lives; this is called indeterminate growth, and it distinguishes plants from most animals. Although certain parts of plants stop growing (e.g., leaves and flowers), others grow continuously—like roots and stems.
36.3K
Cell Specific Gene Expression01:58

Cell Specific Gene Expression

13.3K
Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
13.3K
TGF - β Signaling Pathway01:16

TGF - β Signaling Pathway

7.2K
The TGF-β signaling pathway regulates cell growth, differentiation, adhesion, motility, and development. TGF-β ligands that induce TGF-β signaling are synthesized in their latent form. Several proteases or cell surface receptors such as integrins act upon the latent form, releasing the active ligand. There are three types of mammalian TGF-βs: (TGF-β1, TGF-β2, and TGF-β3) that bind as homodimers or heterodimers to TGF-β receptors. The TGF-β receptors...
7.2K
Somatic to iPS Cell Reprogramming01:29

Somatic to iPS Cell Reprogramming

2.1K
Reprogramming alters the gene expression in somatic cells, transforming them into induced pluripotent stem (iPS) cells over several generations. Scientists can reprogram cells by introducing genes for four transcription factors—Oct4, Sox2, Klf4, and c-Myc (OSKM) by viral or non-viral methods. These factors are also known as Yamanaka factors after Shinya Yamanaka, who first generated iPS cells using mouse skin cells. Yamanaka was awarded the Nobel Prize in Physiology or Medicine in 2012...
2.1K
Glucose Homeostasis: Regulation of Blood Glucose01:02

Glucose Homeostasis: Regulation of Blood Glucose

4.3K
Carbohydrates consumed through foods are converted into glucose, a crucial energy source for the body. In the prandial state, high blood glucose levels stimulate the secretion of insulin from the pancreas. Insulin inhibits hepatic glucose production and stimulates glucose uptake and metabolism by muscle and adipose tissue. The excess glucose is converted into glycogen and stored in the liver and muscles.
During fasting, when blood glucose levels are low, the pancreas secretes glucagon. it...
4.3K
Global Regulatory Systems01:28

Global Regulatory Systems

959
Global regulatory systems in bacteria enable rapid and coordinated responses to environmental changes by integrating sensory inputs with gene expression, ensuring efficient adaptation to fluctuating conditions. Key global regulatory mechanisms include regulons, two-component systems, sigma factors, and secondary messengers.Regulons and Global RegulatorsA regulon is a collection of genes and operons controlled by a common global regulator. These regulators enable bacteria to prioritize resource...
959

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Heat-triggered phospholipid flipping stabilizes plasma membrane fluidity.

Nature·2026
Same author

Allelic variation in UVR8 modulates thermotolerance-yield tradeoffs in plants.

Cell research·2026
Same author

SOC1 clade genes coordinate lateral root development and response to multiple phytohormonal and environmental stress signals in Arabidopsis.

Journal of plant physiology·2026
Same author

The plant epigenome governed by nutrients and metabolism.

Current opinion in plant biology·2025
Same author

OsMATE7-mediated flavonol accumulation regulates pollen tube growth in rice.

The Plant journal : for cell and molecular biology·2025
Same author

Nature variations of OsNLP4 responsible for nitrogen use efficiency divergence in the two rice subspecies.

Nature communications·2025

関連する実験動画

Updated: Apr 30, 2026

A Flexible Low Cost Hydroponic System for Assessing Plant Responses to Small Molecules in Sterile Conditions
11:27

A Flexible Low Cost Hydroponic System for Assessing Plant Responses to Small Molecules in Sterile Conditions

Published on: August 25, 2018

10.7K

グルコース-TORシグナリングは,トランスクリプトームを再プログラムし,メリステームを活性化します.

Yan Xiong1, Matthew McCormack, Lei Li

  • 1Department of Molecular Biology and Centre for Computational and Integrative Biology, Massachusetts General Hospital, and Department of Genetics, Harvard Medical School, Boston, Massachusetts 02114, USA. xiong@molbio.mgh.harvard.edu

Nature
|April 2, 2013
PubMed
まとめ

光合成によるグルコースは,ラパミシン標的 (TOR) 信号伝達を通じて根のメリステムを活性化させ,遺伝子発現と細胞分裂に影響を与え,植物の成長を促します. この栄養信号伝達経路は,植物の発達に極めて重要です.

さらに関連する動画

Inducible, Cell Type-Specific Expression in Arabidopsis thaliana Through LhGR-Mediated Trans-Activation
09:31

Inducible, Cell Type-Specific Expression in Arabidopsis thaliana Through LhGR-Mediated Trans-Activation

Published on: April 19, 2019

9.1K
In Vivo Monitoring of Transcriptional Activity During Metabolic Transition Using a Bioluminescent Reporter in Yeast
06:53

In Vivo Monitoring of Transcriptional Activity During Metabolic Transition Using a Bioluminescent Reporter in Yeast

Published on: February 21, 2025

942

関連する実験動画

Last Updated: Apr 30, 2026

A Flexible Low Cost Hydroponic System for Assessing Plant Responses to Small Molecules in Sterile Conditions
11:27

A Flexible Low Cost Hydroponic System for Assessing Plant Responses to Small Molecules in Sterile Conditions

Published on: August 25, 2018

10.7K
Inducible, Cell Type-Specific Expression in Arabidopsis thaliana Through LhGR-Mediated Trans-Activation
09:31

Inducible, Cell Type-Specific Expression in Arabidopsis thaliana Through LhGR-Mediated Trans-Activation

Published on: April 19, 2019

9.1K
In Vivo Monitoring of Transcriptional Activity During Metabolic Transition Using a Bioluminescent Reporter in Yeast
06:53

In Vivo Monitoring of Transcriptional Activity During Metabolic Transition Using a Bioluminescent Reporter in Yeast

Published on: February 21, 2025

942

科学分野:

  • 植物生物学 植物生物学
  • 分子生物学は分子生物学である.
  • バイオケミストリー バイオケミストリー

背景:

  • メリステムは植物の胚後成長に不可欠であり,幹細胞/祖先細胞を含んでいます.
  • 光合成植物における栄養素シグナル伝達とメリシステム活性化を結びつけるメカニズムは完全に理解されていません.

研究 の 目的:

  • 栄養シグナル伝達,特に光合成からのグルコースが,根のメリスタム活性化をどのように調節するかを調査する.
  • この過程におけるラパミシン標的 (TOR) 信号伝達の役割を明らかにする.

主な方法:

  • 化学的操作と化学遺伝学が,光自己栄養的移行に用いられた.
  • システム,細胞,遺伝子分析が行われました.
  • E2Fa転写因子のTORリン酸化が調査されました.

主要な成果:

  • シュート光合成由来グルコースは,TORシグナル伝達,グリコロシス,ミトコンドリアのバイオエナジェティクスを通じて根のメリステムを活性化します.
  • このプロセスは,直接的なグルコース感知,成長ホルモン,幹細胞維持などとは無関係です.
  • グルコース-TORシグナリングは,様々な細胞プロセスにおける重要な転写再プログラミングを誘発する.
  • TORはE2Faをリン酸化し,従来とは異なるS相遺伝子活性化につながります.

結論:

  • グルコース-TORシグナル伝達は,メリシステム活性化と転写ネットワークを制御することによって,植物発達の中心的な役割を果たします.
  • この経路は,成長のための中央代謝,生合成,臓器間の栄養調整を統合します.
  • 研究結果は,トランスクリプション因子リン酸化による細胞サイクル進行の調節におけるTORの新たな役割を明らかにしている.