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Updated: May 12, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
09:50

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade

Published on: August 14, 2019

9段階のエナチオセレクティブ (-) -ビンコリン全合成

Benjamin D Horning1, David W C MacMillan

  • 1Merck Center for Catalysis at Princeton University, Princeton, New Jersey 08544, USA.

Journal of the American Chemical Society
|April 17, 2013
PubMed
まとめ

アクアミリンアルカロイド (-) - ヴィンコリンの簡潔な合成は,オルガノカタリティックなダイエルス-アルダー,イミニウムサイクライゼーションカスケードを使用して達成されました. この方法は,9つのステップで複雑なテトラサイクルコアを効率的に構築します.

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Regioselective Formation of Enolates

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Synthesis of α-Substituted Carbonyl Compounds: The Stork Enamine Reaction

α-Substituted ketones or aldehydes can be synthesized from enamines by the Stork enamine reaction, named after its pioneer Gilbert Stork. Enamines are useful synthetic intermediates where the lone pair on nitrogen is in conjugation with the C=C bond. They resemble enolate ions, as the resonance forms of both species have a nucleophilic α carbon.
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[3,3] Sigmatropic Rearrangement of Allyl Vinyl Ethers: Claisen Rearrangement

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Stereochemical Effects of Enolization

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Diels–Alder Reaction Forming Cyclic Products: Stereochemistry

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