境界性高血圧の関連性は,標的臓器の変化と冠動脈リスクの上昇と関連している. テカムセー 血圧研究
S Julius1, K Jamerson, A Mejia
1Division of Hypertension, University of Michigan Hospitals, Ann Arbor 48109-0356.
JAMA
|July 18, 1990
まとめ
若年成人における境界性高血圧は一時的なものではありませんし,健康に深刻な影響を及ぼします. この状態は,高血圧,臓器の変化,動脈硬化のリスク要因の増加と関連しています.
科学分野:
- 心臓病学 心臓病学
- 公衆衛生は公衆衛生である.
- 予防医学は,予防的な医療です.
背景:
- 高血圧は心臓血管疾患の主なリスク因子です.
- 高血圧の進化の早期発見と理解は,予防に不可欠です.
- Tecumsehプロジェクトは,心臓血管の健康に関する縦断的なデータを提供しています.
研究 の 目的:
- 若くて健康な集団における境界性高血圧の進行と健康への影響を調査する.
- 高血圧を発症させる早期マーカーおよび関連する危険因子を特定する.
- 境界性高血圧の長期的な影響を評価する.
主な方法:
- 18歳から38歳までの946人の健康な被験者を対象とした長期的研究.
- 診療所および家庭での血圧モニタリング.
- 前腕の抵抗,脳卒中指数,心室のダイアストリック機能を含む心血管のパラメータの評価.
- 冠動脈リスク要因の分析:コレステロール,トリグリセリド,HDL,インスリン,体重.
主要な成果:
- 124人の被験者 (13.1%) が極限高血圧 (臨床BP > 140/90 mm Hg) を示した.
- 境界性高血圧患者は,家庭での高血圧,幼児期および後青春期における高血圧,高血圧の標的臓器の変化を示した.
- 前腕の抵抗,脳卒中指数,下痢性リラクゼーション,高コレステロール,トリグリセリド,インスリン,肥満の異常が観察されました.
結論:
- 若い成人の境界性高血圧は,重大な心血管および代謝異常を伴う持続的な状態です.
- 境界性高血圧の早期発見は,動脈硬化症の予測要因と関連しているため,正当化されています.
- 予防的な心血管疾患のケアには,境界性高血圧に対する臨床的注意が必要である.
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