orofacialのリズムの階層は,ウィスキーと呼吸を通して明らかになりました
Jeffrey D Moore1, Martin Deschênes, Takahiro Furuta
1Department of Physics, University of California at San Diego, 9500 Gilman Drive, La Jolla, California 92093, USA.
Nature
|April 30, 2013
まとめ
ネズミの鳴き声や嗅ぎ声は,腹中髄の呼吸器センターによって調整されます. この神経回路は,ひげをひそめるような顔の動きが呼吸パターンと同期することを保証します.
科学分野:
- 神経科学は神経科学である.
- 行動生物学 行動生物学
- モーター・コントロール・コントロール
背景:
- 鳴き声と嗅ぎ声は,歯類における重要な探検行動である.
- これらのオロファシアルモーターパターンを調整する神経機構は十分に理解されていません.
研究 の 目的:
- 協調したぎと嗅ぎの行動の神経制御を調査する.
- これらの動きと呼吸の生成と同期を担当する脳の領域を特定する.
主な方法:
- アナトミック・トレーシング・テクニック
- ネズミの探索行動に関する行動分析.
- ニューロンの活動に関する電気生理学的記録
- 神経回路の薬理学的な操作
主要な成果:
- リズム的にビブリサエの伸縮を駆動する特定の腹腔髄領域を特定しました.
- プレ・ボッツィンガー複合体は,インスピレーション中にこの領域からのニューロンの出力をリセットすることを実証しました.
- 呼吸サイクルとスウィーキング/スニッフィングの調整の間の直接的なリンクを確立し,高周波スニッフィングの1対1の関係を示した.
結論:
- 静脈中枢にある呼吸器センターは,鼻をひそめ,鼻を嗅ぐことを調整する.
- プレ・ボツィンガー複合体は,オロファシアルモーターパターンの重要なタイミングシグナルとして機能する.
- 呼吸器の核は,呼吸を調整する行動のマスタークロックとして機能する.
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