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Updated: May 11, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

高度にエナチオセレクティブなジルコニウム触媒によるアミノアルケンのサイクリング

Kuntal Manna1, William C Everett, George Schoendorff

  • 1Department of Chemistry and U.S. Department of Energy Ames Laboratory, Iowa State University, Ames, Iowa 50011, USA.

Journal of the American Chemical Society
|May 2, 2013
PubMed
まとめ

チラルのN-ヘテロサイクリックアミンは,新しいグループ4複合体を用いてアミノアルケンの触媒サイクリングによって合成されます. この高度にエナチオセレクティブなプロセスは,協調した移行状態を明らかにし,効率的な非対称合成を可能にします.

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