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Updated: Apr 5, 2026

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mTORキナーゼの構造,メカニズム,および調節について

Haijuan Yang1, Derek G Rudge, Joseph D Koos

  • 1Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

Nature
|May 3, 2013
PubMed
まとめ

ラパミシン (mTOR) キナーゼ構造の哺乳類の標的は,本質的に活性な構成を明らかにします. その活動は,FRBドメインと阻害ヘリックスによって制御される,制限されたアクティブサイトアクセスによって規制されます.

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