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Updated: May 11, 2026

Hypoxia Alters miRNAs Levels Involved in Non-Mendelian Inheritance of Autism Spectrum Disorder in Mice
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EGFRは,AGO2のリン酸化により,低酸素への反応として,マイクロRNAの成熟を調節する

Jia Shen1, Weiya Xia, Yekaterina B Khotskaya

  • 1Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.

Nature
|May 3, 2013
PubMed
まとめ

表皮成長因子受容体 (EGFR) は,アルゴナウト2 (AGO2) をリン酸化することによって,低酸素期におけるマイクロRNA (miRNA) の成熟を抑制する. このEGFR-AGO2相互作用は,腫瘍細胞の生存率と侵襲性に影響を与え,潜在的な臨床的洞察を提供します.

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Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions09:17

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions

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