A/C,調,MKL1-SRF調.

Chin Yee Ho1, Diana E Jaalouk, Maria K Vartiainen

  • 1Cornell University, Weill Institute for Cell and Molecular Biology/Department of Biomedical Engineering, Ithaca, New York 14853, USA.

Nature
|May 7, 2013
PubMed
まとめ

LMNA遺伝子の変異は,核包膜タンパク質に影響を及ぼし,ラミノパシーを引き起こす. この研究では,ラミンA/Cとエメリンは,アクチンダイナミクスを通じて遺伝子発現を調節し,心臓機能に影響を及ぼすことを明らかにしました.

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