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Updated: May 11, 2026

Identification of EGFR and RAS Inhibitors using Caenorhabditis elegans
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KRAS-PDEδ相互作用の小分子阻害は,腫瘍性KRASシグナリングを損なう

Gunther Zimmermann1, Björn Papke, Shehab Ismail

  • 1Department of Chemical Biology, Max Planck Institute of Molecular Physiology, D-44227 Dortmund, Germany.

Nature
|May 24, 2013
PubMed
まとめ

研究者は,KRAS-PDEδ相互作用を妨害する小分子を開発し,腫瘍性RAS信号伝達を抑制し,臓がん細胞の増殖を抑制する新しい戦略を提供しました.

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