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Updated: May 10, 2026

Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis
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ソニック・ヘッジホッグ経路の小分子調節器の発見

Giannina I Schaefer1, José R Perez, Jeremy R Duvall

  • 1Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.

Journal of the American Chemical Society
|June 4, 2013
PubMed
まとめ

研究者らは,ソニック・ヘッジホッグ (Shh) 信号経路を標的とした2つの新しい小分子阻害剤BRD50837とBRD9526を発見した. これらの化合物は,Shh経路の調節と癌などの疾患におけるその役割の研究のための新しいメカニズムを提供します.

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