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Updated: May 10, 2026

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
05:37

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

大規模な量子化学計算を用いて得られた異なるDNAグアニン四重複幹トポロジーの相対的な安定性

Jiří Šponer1, Arnošt Mládek, Naďa Špačková

  • 1Institute of Biophysics, Academy of Sciences of the Czech Republic, Královopolská 135, 612 65 Brno, Czech Republic. sponer@ncbr.muni.cz

Journal of the American Chemical Society
|June 8, 2013
PubMed
まとめ

この研究では,正確な量子力学 (QM) 計算を使用して,グアナイン四重複 (G-DNA) 構造の安定性を予測しました. QM計算は,標準的な分子力学力場と比較して有意な差異を明らかにし,G-DNA幹の安定性の理論的予測を改善しました.

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