分泌されるPTENフォスファタゼが細胞に入り,信号伝達と生存を変化させる

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Updated: May 10, 2026

Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors
08:45

Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors

Published on: July 17, 2020

Benjamin D Hopkins1, Barry Fine, Nicole Steinbach

  • 1Department of Oncological Sciences, Icahn School of Medicine at Mount Sinai, 1470 Madison Avenue, New York, NY 10029, USA.

Science (New York, N.Y.)
|June 8, 2013
PubMed
まとめ

研究者らは,PTEN腫瘍抑制剤の新しい変種であるPTEN-Longを発見しました. この変種は細胞に侵入し,がんの成長を抑制し,潜在的な新しいがん治療法を提供することができます.

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