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Updated: Sep 7, 2026

Investigating Mast Cell Secretory Granules; from Biosynthesis to Exocytosis
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Published on: January 26, 2015

マスト細胞は,既成形および免疫学的に誘導可能なTNF-alpha/cachectinの両方の源である

J R Gordon1, S J Galli

  • 1Department of Pathology, Beth Israel Hospital, Boston, Massachusetts 02215.

Nature
|July 19, 1990
PubMed
まとめ

マウスマスト細胞は,組織的に腫瘍死滅因子アルファ (TNF-alpha) を生成し,放出する. IgE依存活性化は,この放出を促進し,マスト細胞を宿主防御とアレルギー疾患に関与するTNF-αの主要な源として識別します.

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