インフルエンザAウイルスH7N9ヘマグルチニンのグリカン受容体結合

Kannan Tharakaraman1, Akila Jayaraman, Rahul Raman

  • 1Department of Biological Engineering, Koch Institute of Integrative Cancer Research, Infectious Diseases Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.

Cell
|June 11, 2013
PubMed
まとめ

H7N9インフルエンザウイルスはヒトの受容体への結合が限られているが,単一の変異により,上呼吸道における広範な結合が可能になる. この発見は,潜在的なパンデミック感染拡大とワクチンの有効性に影響を及ぼします.

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