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Updated: May 1, 2026

Visualization of Endoplasmic Reticulum Subdomains in Cultured Cells
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折りたたむタンパク質をカプセル化しているGroEL/ESを視覚化します

Dong-Hua Chen1, Damian Madan, Jeremy Weaver

  • 1Verna and Marrs McLean Department of Biochemistry and Molecular Biology, National Center for Macromolecular Imaging, Baylor College of Medicine, Houston, TX 77030, USA.

Cell
|June 11, 2013
PubMed
まとめ

GroEL/ESのチャペロニン系は,タンパク質の折り畳みを促進する. 研究者は,RuBisCOのような基板タンパク質がGroEL-GroES腔内に結合する方法を視覚化するために,冷凍-EMを使用し,封じ込め中に重要な構造変化を明らかにしました.

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