母親の肥満と早産のリスク
Sven Cnattingius1, Eduardo Villamor, Stefan Johansson
1Clinical Epidemiology Unit, T2, Department of Medicine Solna, Karolinska University Hospital, Karolinska Institutet, SE-171 76 Stockholm, Sweden. sven.cnattingius@ki.se
JAMA
|June 13, 2013
まとめ
妊娠初期における母親の過剰体重と肥満は,早産のリスク,特に極めて早産のリスクを大幅に高めます. これらの発見は,不良妊娠結果を減らすために体重管理の重要性を強調しています.
科学分野:
- 産婦人科と産婦人科を担当しています.
- 公衆衛生は公衆衛生である.
- перинатаル流行病学について
背景:
- 胎児の早産は,乳児死亡率と発病率の主な原因である.
- 肥満は早産の危険因子として知られていますが,特定のサブタイプとの関連は不明です.
研究 の 目的:
- 妊娠初期におけるボディマス指数 (BMI) と早産のリスクとの関係を調査する.
- 異なる妊娠年齢と早産のサブタイプにおけるこれらの関連性を分析する.
主な方法:
- スウェーデンの医療出産記録 (1992年−2010年) のデータを利用した人口ベースのコホート研究.
- 妊娠初期に記録された生きたシングルトン出産を含む.BMI.
- 複数の母体および妊娠要因に調整した自発的および医学的に示された早産の分析.
主要な成果:
- BMIの上昇は,極端な,非常に,および適度な早産のリスクが高いことと関連していました.
- 超重量と肥満は,極度の早産のリスクが最も高いことを示しました.
- 肥満の女性 (BMI ≥30) は,自発的な極度の早産のリスクが有意に上昇し,リスクはBMIとともに増加しました.
結論:
- 妊娠初期における母親の過剰体重と肥満は,早産のリスク,特に極端な早産のリスクの増加と関連しています.
- この結果は,これらの関連性を確認するために,多様な集団でのさらなる研究が必要であることを強調しています.
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