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Updated: May 10, 2026

Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells
13:38

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Published on: January 18, 2017

BRAF変異状態によるアスピリンの使用と結腸直腸がんのリスク

Reiko Nishihara1, Paul Lochhead, Aya Kuchiba

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.

JAMA
|June 27, 2013
PubMed
まとめ

定期的なアスピリンの使用は,BRAF-ワイルド型腫瘍の患者でも,BRAF-変異腫瘍の患者では結腸直腸がんのリスクを下げる. これは,BRAF変異性大腸細胞がアスピリンに敏感性が低い可能性を示唆し,臨床的影響に関するさらなる調査を正当化しています.

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