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Fe-Sクラスター生物合成は,ROSの少ない死亡経路でアミノグリコシドの吸収を制御します

Benjamin Ezraty1, Alexandra Vergnes, Manuel Banzhaf

  • 1Laboratoire de Chimie Bactérienne, Aix-Marseille Université, CNRS, UMR 7283, Institut de Microbiologie de la Méditerranée, 31 Chemin Joseph Aiguier, 13009 Marseille France.

Science (New York, N.Y.)
|July 2, 2013
PubMed
まとめ

細菌滅菌抗生物質は,殺菌するために活性酸素種 (ROS) を必要としません. 鉄硫黄 (Fe-S) クラスターは,細胞の吸収を可能にすることで,アミノグリコシド抗生物質の有効性にとって不可欠です.

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