関連する実験動画

Updated: May 10, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
09:08

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

菌類の非還元ポリケチド合成酵素のチオエステラーゼドメインは,組合せ生物合成の際に決定ゲートとして作用する

Yuquan Xu1, Tong Zhou, Shuwei Zhang

  • 1Natural Products Center, School of Natural Resources and the Environment, The University of Arizona, 250 East Valencia Road, Tucson, Arizona 85706, USA.

Journal of the American Chemical Society
|July 5, 2013
PubMed
まとめ

チオエストラーゼ (TE) ドメインは,真菌ポリケチドの放出を制御し,製品形成を決定する決定ゲートとして作用します. TEドメインの慎重な選択は,組合せ生物合成による新しい"非自然な製品"の設計に不可欠です.

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