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Updated: May 10, 2026

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癌細胞のマイクロ核の核封筒の壊滅的な崩壊

Emily M Hatch1, Andrew H Fischer, Thomas J Deerinck

  • 1Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, 10010 N. Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|July 6, 2013
PubMed
まとめ

マイクロ核 (MN) は,核封筒 (NE) の欠陥により,核機能を損ない,DNA損傷を引き起こすため,インターフェーズ中に不可逆的に崩壊することがあります. このNE崩壊はゲノム不安定と関連しており,がんのバイオマーカーとして機能する可能性があります.

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