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Updated: May 9, 2026

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry
10:24

Defining Hsp33's Redox-regulated Chaperone Activity and Mapping Conformational Changes on Hsp33 Using Hydrogen-deuterium Exchange Mass Spectrometry

Published on: June 7, 2018

シェパロントリガー因子によるタンパク質の構成的探求の再構成

Alireza Mashaghi1, Günter Kramer, Philipp Bechtluft

  • 1FOM institute AMOLF, Science Park 104, 1098 XG Amsterdam, The Netherlands.

Nature
|July 9, 2013
PubMed
まとめ

E. coli のトリガーファクター (TF) チャペロンは,部分的に折りたたまれたタンパク質に結合し,それらを安定させ,ネイティブタンパク質の折りたたみを促進します. このチャペロン作用は,誤った折り畳みを防止し,細胞タンパク質ホメオスタシスの決定的な役割を果たします.

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