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Updated: May 9, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

エンジニアリングされたサイクロチドによるp53腫瘍抑制経路のインビボ活性化

Yanbin Ji1, Subhabrata Majumder2, Melissa Millard1

  • 1Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90033, USA.

Journal of the American Chemical Society
|July 16, 2013
PubMed
まとめ

エンジニアリングされたサイクロチドはHdm2とHdmXを標的とし,がん細胞の生存を抑制します. この新しいMCo-PMIペプチドは,野生型のp53腫瘍に対する安定性と有効性を示し,有望ながん治療を提供している.

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