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Updated: May 5, 2026

Lighting Up the Pathways to Caspase Activation Using Bimolecular Fluorescence Complementation
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Sp1転写因子は,カスペーゼ依存およびカスペーゼ独立のアポプトシス経路を調整する

Takashi Hirose1, H Robert Horvitz

  • 1Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

Nature
|July 16, 2013
PubMed
まとめ

単一の転写因子SPTF-3は,C. elegansの発達におけるカスパーゼ依存性およびカスパーゼ独立性アポトーシス経路の両方を制御する. この発見は,細胞型特異のプログラム細胞死のための二価調節節節を明らかにしています.

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