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Nephrotic Syndrome I : Introduction
01:24

Nephrotic Syndrome I : Introduction

Published on: June 19, 2025

476

クラスBのGPCRコルチコトロピン解放因子受容体1の構造

Kaspar Hollenstein1, James Kean, Andrea Bortolato

  • 1Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City AL7 3AX, UK.

Nature
|July 19, 2013
PubMed
まとめ

研究者らは,コルチコトロピン放出因子受容体1型トランスメブラン領域の結晶構造を決定した. これは,クラスBのGタンパク質結合受容体 (GPCRs) についての洞察を提供し,脳および代謝疾患のための薬剤設計を支援します.

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Nephrotic Syndrome I : Introduction01:24

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Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
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