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Nervous Tissue: Glial Cells01:31

Nervous Tissue: Glial Cells

Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial cells that interact...
Glial Cells01:04

Glial Cells

Overview
The Synapse02:47

The Synapse

Neurons communicate with one another by passing on their electrical signals to other neurons. A synapse is the location where two neurons meet to exchange signals. At the synapse, the neuron that sends the signal is called the presynaptic cell, while the neuron that receives the message is called the postsynaptic cell. Note that most neurons can be both presynaptic and postsynaptic, as they both transmit and receive information.
Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

Ligand-Gated Ion Channel Receptor: Gating Mechanism

Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
Nervous Tissue: Myelin01:25

Nervous Tissue: Myelin

The myelin sheath is a multilayered lipid and protein covering that insulates the axon of a neuron, enhancing the speed of nerve impulse conduction. Axons without this sheath are referred to as unmyelinated. Two types of neuroglia, Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS) are responsible for producing myelin sheaths.
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...
Synaptic Signaling01:12

Synaptic Signaling

Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.

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Updated: May 9, 2026

Dissection and Isolation of Murine Glia from Multiple Central Nervous System Regions
08:00

Dissection and Isolation of Murine Glia from Multiple Central Nervous System Regions

Published on: June 4, 2020

膠質はシナプスの分布を隠蔽している.

Laura E Clarke1, Ben A Barres

  • 1Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA. lclarke2@stanford.edu

Cell
|July 23, 2013
PubMed
まとめ
この要約は機械生成です。

膠質細胞は,神経細胞の軸索を正しいターゲットに導く上で重要な役割を果たします. この研究は,神経系の発達中に適切なシナプス接続を維持するにおけるグリアの機能を強調しています.

さらに関連する動画

Application of MultiColor FlpOut Technique to Study High Resolution Single Cell Morphologies and Cell Interactions of Glia in Drosophila
08:30

Application of MultiColor FlpOut Technique to Study High Resolution Single Cell Morphologies and Cell Interactions of Glia in Drosophila

Published on: October 20, 2017

Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number
18:11

Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number

Published on: November 16, 2010

関連する実験動画

Last Updated: May 9, 2026

Dissection and Isolation of Murine Glia from Multiple Central Nervous System Regions
08:00

Dissection and Isolation of Murine Glia from Multiple Central Nervous System Regions

Published on: June 4, 2020

Application of MultiColor FlpOut Technique to Study High Resolution Single Cell Morphologies and Cell Interactions of Glia in Drosophila
08:30

Application of MultiColor FlpOut Technique to Study High Resolution Single Cell Morphologies and Cell Interactions of Glia in Drosophila

Published on: October 20, 2017

Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number
18:11

Quantifying Synapses: an Immunocytochemistry-based Assay to Quantify Synapse Number

Published on: November 16, 2010

科学分野:

  • 神経科学は神経科学である.
  • 発達生物学 発達生物学について
  • 細胞生物学 細胞生物学

背景:

  • アクソン誘導は,機能的なニューラル回路の確立に不可欠です.
  • 軸索の位置を適切に維持することは,神経系の発達において極めて重要です.
  • 精密な配線と接続におけるグリアル細胞の役割は,現在進行中の研究分野です.

研究 の 目的:

  • 適切なシナプス結合の維持における膠質細胞の役割を調査する.
  • 発達の過程でグリアが軸索の位置づけに影響を与えるメカニズムを解明する.

主な方法:

  • 研究は,バイオイメージングまたはモデル生物における遺伝子操作技術を含む可能性が高い.
  • 特定の膠質機能の存在または欠如における軸索経路発見とシナプス形成の分析.

主要な成果:

  • シャオ et al. シャオ et al. シャオと仲間たち (2013) は,正しいシナプス接続性の維持において,膠質の重要な機能を特定した.
  • Gliaは,成長過程で軸索の正確な位置を維持するのに積極的に貢献します.

結論:

  • 膠質細胞は,単にサポートするだけでなく,神経系の正確な配線に積極的に参加します.
  • 膠質の役割を理解することは,神経回路形成と潜在的な発達障害を理解する鍵です.