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Updated: May 9, 2026

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
10:37

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs

Published on: May 10, 2018

哺乳類のタンパク質合成の開始とmRNAスキャンメカニズム

Ivan B Lomakin1, Thomas A Steitz

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520-8114, USA. ivan.lomakin@yale.edu

Nature
|July 23, 2013
PubMed
まとめ

研究者は,真核細胞の翻訳開始の重要なステップを視覚化し,小さなリボソームサブユニットがメッセンジャーRNA (mRNA) と結合し,タンパク質合成を開始するためにスキャンする方法を明らかにしました. これらの発見は,開始因子とmRNAスキャンメカニズムの役割を明確にします.

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