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Updated: May 9, 2026

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
08:56

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions

Published on: November 30, 2022

化学C−H酸化による生物変換の補完:複合医薬品における三次アミンの銅触媒による酸化

Julien Genovino1, Stephan Lütz, Dalibor Sames

  • 1Global Discovery Chemistry, Novartis Institutes for Biomedical Research, 250 Massachusetts Avenue, Cambridge, Massachusetts 02139, USA.

Journal of the American Chemical Society
|July 24, 2013
PubMed
まとめ

研究者らは,薬物の代謝物を迅速に生成するための新しい化学的方法を開発し,薬物の発見と開発のために伝統的な生物変換と化学的酸化の限界を克服しました.

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