エピレプシーにおける早期死亡率と精神疾患併発症の役割:全人口研究
Seena Fazel1, Achim Wolf, Niklas Långström
1University of Oxford, Department of Psychiatry, Warneford Hospital, Warneford Lane, Headington, Oxford, UK.
Lancet (London, England)
|July 26, 2013
まとめ
精神科併発症は,特に自殺や事故などの外的原因による,患者の早期死亡リスクを大幅に増加させる. 精神的健康への取り組みは,のケアを改善し,予防可能な死亡を減らすために不可欠です.
科学分野:
- 神経学 神経学とは
- 精神科医は精神病を患っている.
- 公衆衛生は公衆衛生である.
背景:
- はより高い早期死亡率と関連しているが,精神疾患の役割は不明である.
- 自殺,事故,暴行などの外部原因は,この死亡率に大きく貢献しています.
- エピレプシー,精神科併発症,死亡率の相互作用を理解することは,効果的な管理に不可欠です.
研究 の 目的:
- エピレプシー患者における外部原因による早期死亡の発生率とリスクを評価する.
- これらの死亡リスクに対する精神科併発症の影響を調査する.
- エピレプシー患者における死亡リスクと一般集団の対照群および影響を受けていない兄弟姉妹を比較する.
主な方法:
- スウェーデンの全国的なコホート研究 (1954年 - 2009年) には,の患者69,995人が含まれていました.
- 一般集団の対照群660,869人と,影響を受けていない兄弟姉妹81,396人と比較した結果です.
- 感度分析では,性別,年齢,発作タイプ,精神科併発症,診断から経過した時間による変動が検討されました.
主要な成果:
- の患者は,対照群と比較して,早死の可能性が11.1倍に増加しました.
- 外部原因による死亡は15.8%を占め,自動車以外の事故 (aOR 5.5) と自殺 (aOR 3.7) の確率が高い.
- 併発性精神疾患,特にうつ病および薬物乱用は,における外因による死亡率と強く関連していました.
結論:
- 外部原因による早期死亡率の減少は,の管理における優先事項です.
- 精神疾患併発症は,に関連した早期死亡率の重要な要因である.
- これらの死亡を防ぐために,保健サービスと公衆衛生戦略の評価が必要です.
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