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Updated: May 9, 2026

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling
09:33

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling

Published on: March 20, 2018

プチダレドキシンとの複合体におけるP450camの構成は酸化状態に依存しています

William K Myers1, Young-Tae Lee, R David Britt

  • 1Department of Chemistry, University of California, Davis, One Shields Avenue, Davis, California 95616, USA.

Journal of the American Chemical Society
|August 2, 2013
PubMed
まとめ

ヘムモノオキシゲナーゼP450camは,そのレドックスパートナーであるプチダレドキシン (Pdx) と結合すると形状が変化します. 減少したPdx結合は,閉じた酵素状態を好み,基質認識と電子移転のモデルをサポートします.

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