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Updated: May 9, 2026

In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines
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In Vitro Chemical Mapping of G-Quadruplex DNA Structures by Bis-3-Chloropiperidines

Published on: May 12, 2023

テロメスタチンの誘導体と結合したヒトのテロメリックG-四重複の分子内 (3 + 1) の溶液構造

Wan Jun Chung1, Brahim Heddi, Masayuki Tera

  • 1School of Physical and Mathematical Sciences, Nanyang Technological University , Singapore.

Journal of the American Chemical Society
|August 6, 2013
PubMed
まとめ

研究者らは,テロメスタチンの誘導体で複合されたヒトのテロメアG四重複合体の最初の高解像度構造を明らかにした. この発見は,G-四重複構造を標的とした新しい抗癌薬の開発を進めています.

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